Articles Scientifiques

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Articles scientifiques, subventionnés par la Fondation Universitaire.

Ce qui suit est une liste d'articles scientifiques qui ont été subventionnés par la Fondation Universitaire. Les articles sont triés par année de publication et par titre.

Natacha Biset, Wies Kestens, Dominique Detemmerman, Murielle Lona, Güngör Karakaya, Ann Ceuppens, Stéphanie Pochet and Carine De Vriese

Biset, N.; Kestens, W.; Detemmerman, D.; Lona, M.; Karakaya, G.; Ceuppens, A.; Pochet, S.; De Vriese, C. (2022) Analysis of the Consumption of Drugs Prescribed for the Treatment of Asthma in Belgian Children. Int. J. Environ. Res. Public Health, 19, 548.

Abstract: (1) Asthma is one of the most common chronic diseases in the world among children. The main purpose of this study was to analyze the consumption of asthma medications in order to investigate asthma in children (2–18 years) and the association with health care consumption; (2) a retrospective study using anonymized administrative data for 2013–2018 from the third largest Belgian health insurer was conducted; (3) in 2018, 12.9% of children received at least one asthma medication and 4.4% received at least two packages with a minimum of 30 days between purchases.

Noora Taipale, Laurent Chiotti, Veerle Rots

Taipale N, Chiotti L, Rots V (2022) Why did hunting weapon design change at Abri Pataud? Lithic use-wear data on armature use and hafting around 24,000–22,000 BP. PLoS ONE 17(1): e0262185.

Abstract : Projectile technology is commonly viewed as a significant contributor to past human subsistence and, consequently, to our evolution. Due to the allegedly central role of projectile weapons in the food-getting strategies of Upper Palaeolithic people, typo-technological changes in the European lithic record have often been linked to supposed developments in hunting weaponry. Yet, relatively little reliable functional data is currently available that would aid the detailed reconstruction of past weapon designs.

Marine Pyl, Bruno Danis, François Oberhaensli, Angus Taylor, Peter Swarzenski, Marc Metian

Pyl, M., Danis, B. et al. (2021) An effective method to assess the sorption dynamics of PCB radiotracers onto plastic and sediment microparticles.  MethodsX, Volume 8, 101395.

Abstract : One important aspect of marine plastic pollution is that small particles are ubiquitously present in seawater and can transport a large variety of co-contaminants. The sorption-desorption kinetics of these co-contaminants sorbed to microplastics (MPs) are not fully understood, partially due to the lack of any standardised procedures between studies. The present work aims at describing a new and efficient method to investigate the sorption of co-contaminants onto different types of particles using proven radiotracer techniques.

Alexandre Heeren, Séverine Lannoy, Charlotte Coussement et al.

Heeren, A., Lannoy, S., Coussement, C. et al. A network approach to the five-facet model of mindfulness. Sci Rep 11, 15094 (2021).

Abstract : Despite the large-scale dissemination of mindfulness-based interventions, debates persist about the very nature of mindfulness. To date, one of the dominant views is the five-facet approach, which suggests that mindfulness includes five facets (i.e., Observing, Describing, Nonjudging, Nonreactivity, and Acting with Awareness). However, uncertainty remains regarding the potential interplay between these facets. In this study, we investigated the five-facet model via network analysis in an unselected sample (n = 1704).

Emilio Brunetti, Lionel Marcelis, Fedor E. Zhurkin, Michel Luhmer, Ivan Jabin, Olivia Reinaud and Kristin Bartik

Brunetti, E., Bartik, K. et al. (2021) A Water Molecule Triggers Guest Exchange at a Mono-Zinc Centre Confined in a Biomimetic Calixarene Pocket: a Model for Understanding Ligand Stability in Zn Proteins. in Chemistry. DOI: 10.1002/chem.202102184

Abstract: In this study, the ligand exchange mechanism at a biomimetic ZnII centre, embedded in a pocket mimicking the possible constrains induced by a proteic structure, is explored. The residence time of different guest ligands (dimethylformamide, acetonitrile and ethanol) inside the cavity of a calix[6]arene-based tris(imidazole) tetrahedral zinc complex was probed using 1D EXchange SpectroscopY NMR experiments.

Meenakshi Poti, Seh Ling Long, Mohd Uzair Rusli, Jarina Mohd Jani, Jean Hugé and Farid Dahdouh-Guebas

Poti, M., S. L. Long, M. U. Rusli, J. Mohd Jani, J. Hugé, and F. Dahdouh-Guebas (2021). Changing trends and perceptions of sea turtle egg consumption in Redang Island, Malaysia. Ecology and Society 26(4):14.

ABSTRACT : Sea turtles have been exploited at unsustainable rates globally. In Malaysia, their populations have faced serious declines because of diverse anthropogenic stressors including turtle egg consumption. Redang Island, off the northeast coast of Peninsular Malaysia, is an important rookery for green sea turtles (Chelonia mydas) in Southeast Asia. The local community has depended on turtle eggs as a food and livelihood source for decades. Owing to the precipitous decline in sea turtles, the main nesting beaches became legally protected in 2007.

Stefanie Brock, Tim Vanderhasselt, Sietske Vermaning, Kathelijn Keymolen, Luc Régal, et al.

Brock S, Vanderhasselt T, Vermaning S, et al. (2021) Defining the phenotypical spectrum associated with variants in TUBB2A.  Journal of Medical Genetics, 58:33–40. doi:10.1136/jmedgenet-2019-106740

Abstract : Background Variants in genes belonging to the tubulin superfamily account for a heterogeneous spectrum of brain malformations referred to as tubulinopathies. Variants in TUBB2A have been reported in 10 patients with a broad spectrum of brain imaging features, ranging from a normal cortex to polymicrogyria, while one patient has been reported with progressive atrophy of the cerebellar vermis.

Alexandre Kuhn, Serge Aron and Olivier J. Hardy
Kuhn A, Aron S and Hardy OJ (2021) Detection of Cryptic Sex in Automictic Populations: Theoretical Expectations and a Case Study in Cataglyphis Desert Ants. Front. Ecol. Evol. 9:741959. doi: 10.3389/fevo.2021.741959
Reproductive strategies are diverse and a whole continuum of mixed systems lies between strict sexuality and strict clonality (apomixis), including automixis, a parthenogenetic mode of reproduction involving a meiosis and increasing homozygosity over generations. These various systems impact the genetic structure of populations, which can therefore be used to infer reproductive strategies in natural populations. Here, we first develop a mathematical model, validated by simulations, to predict
Julie Gheysen, Matthieu Marteleur, Camille van der Rest, Aude Simar

Gheysen, J., Marteleur, M., van der Rest, C., Simar, A. (2021) Efficient optimization methodology for laser powder bed fusion parameters to manufacture dense and mechanically sound parts validated on AlSi12 alloy. Materials & Design, Volume 199, 109433.

Abstract : The main drawback of laser powder bed fusion (L-PBF), commonly called selective laser melting (SLM) is the high porosity which may lead to an early failure of the parts. To minimize it, the L-PBF parameters need to be optimized focusing on the laser power, scanning speed and hatching space. However, no standard guideline exists. In this study, an efficient and cost-effective methodology is developed and validated on AlSi12. This innovative methodology brings together single scan tracks (SST), macroscopic properties analysis and design of experiments (DOE).

Roxane Verdikt † , Olivier Hernalsteens and Carine Van Lint

Verdikt, R. † , Hernalsteens, O and Van Lint, C. (2021) Epigenetic Mechanisms of HIV-1 Persistence. Vaccines, 9, 514.

Abstract : Eradicating HIV-1 in infected individuals will not be possible without addressing the persistence of the virus in its multiple reservoirs. In this context, the molecular characterization of HIV-1 persistence is key for the development of rationalized therapeutic interventions. HIV-1 geneexpression relies on the redundant and cooperative recruitment of cellular epigenetic machineries to cis-regulatory proviral regions.

Manon Pigeolet, Saiful Imam, Gheorghe Cristian Ninulescu, Shafiul Kabir, Pierre R. Smeesters, Hasib Mahmud

Pigeolet, M. et al. (2021) Evaluation of a surgical treatment algorithm for neglected clubfoot in low‑resource settings. International Orthopaedics.

Purpose :
Idiopathic clubfoot affects approximately 1/1000 alive-born infants, of whom 80–91% are born in low- or middleincome countries (LMICs). This retrospective study aimed to evaluate the morphological, functional, and social outcomes in patients with neglected clubfoot in rural Bangladesh, after receiving surgical treatment.

Samuel Vanden Abeele, Steven B Janssens, Rosalía Piñeiro, Olivier J Hardy

Vanden Abeele et al. (2021) Evidence of past forest fragmentation in the Congo Basin from the phylogeography of a shade-tolerant tree with limited seed dispersal: Scorodophloeus zenkeri (Fabaceae, Detarioideae) BMC Ecology and Evolution

Background: Comparative phylogeographic studies on rainforest species that are widespread in Central Africa often reveal genetic discontinuities within and between biogeographic regions, indicating (historical) barriers to gene flow, possibly due to repeated and/or long-lasting population fragmentation during glacial periods according to the forest refuge hypothesis. The impact of forest fragmentation seems to be modulated by the ecological amplitude and dispersal capacities of each species, resulting in different demographic histories.

Juan Guillermo Santos Macías, Chola Elangeswaran, Lv Zhao, Jean-Yves Buffière, Brecht Van Hooreweder, Aude Simar

Santos Macías, Elangeswaran, Zhao et al. (2021) Fatigue crack nucleation and growth in laser powder bed fusion AlSi10Mg under as built and post-treated conditions. Materials & Design 210

Abstract : Numerous efforts have been devoted to produce reliable additive manufactured (AM) materials for structural applications. However, the critical fatigue issue poses a significant hurdle in relation to the nature of this production method. Despite the  relative flexibility of the laser powder bed fusion (LPBF) AM process, there exists a limitation in the possibility of tailoring parameters to obtain a satisfactory combination of porosity and surface roughness for adequate fatigue resistance.

Jeroen Van Schependom, Diego Vidaurre, Lars Costers, Martin Sjøgård, Diana M Sima, Dirk Smeets, Marie Beatrice D'hooghe, Miguel D'haeseleer, Gustavo Deco, Vincent Wens, Xavier De Tiège, Serge Goldman, Mark Woolrich, Guy Nagels

Van Schependom, J. et al. (2021) Increased brain atrophy and lesion load is associated with stronger lower alpha MEG power in multiple sclerosis patients NeuroImage: Clinical Volume 30, 102632 DOI: 10.1016/j.nicl.2021.102632

Abstract: In multiple sclerosis, the interplay of neurodegeneration, demyelination and inflammation leads to changes in neurophysiological functioning. This study aims to characterize the relation between reduced brain volumes and spectral power in multiple sclerosis patients and matched healthy subjects. During resting-state eyes closed, we collected magnetoencephalographic data in 67 multiple sclerosis patients and 47 healthy subjects, matched for age and gender. Additionally, we quantified different brain volumes through magnetic resonance imaging (MRI).

Isabel S. Schiller, Dominique Morsomme, Malte Kob and Angélique Remacle

Schiller I., Morsomme D., Kob M. & Remacle A. (2021) Listening to a Dysphonic Speaker in Noise May Impede Children’s Spoken Language Processing in a Realistic Classroom Setting. Language, Speech, and Hearing Services in Schools Vol. 52, 396–408.

Purpose The aim of this study was to investigate children's processing of dysphonic speech in a realistic classroom setting, under the influence of added classroom noise.