The concept of value seems to have capital importance both in the scientific literature and in various heritage actors’ professional discourse. The actions undertaken to develop the built environment inherited from previous generations seem to depend on thevalue we assign it. In this essay, the concepts of value, assessor, and heritage assessment are discussed. Two historical contexts are compared: the classical axiology of the 19th century based on the Enlightenment search for rationality and the typologies of contemporary values struggling with complexity.

Characterizing the early development of the human brain is critical from both fundamental and clinical perspectives. However, existing neuroimaging techniques are either not well suited to infants or have limited spatial or temporal resolution. The advent of optically pumped magnetometers (OPMs) has revolutionized magnetoencephalography (MEG) by enabling wearable and thus more naturalistic recordings while maintaining excellent sensitivity and spatiotemporal resolution. Nevertheless, its adaptation to studying neural activity in infancy poses several challenges.

Cuneiform tablets were a primary writing medium in the ancient Near East from the late fourth millennium BCE to the first century CE. Although these clay tablets were durable for daily use, prolonged burial over millennia has made them vulnerable to salt damage. Fluctuations in temperature and humidity cause the migration of salts to the surface of the tablets, damaging them and covering the inscriptions, making the text unreadable.

Research increasingly highlights that more nascent entrepreneurs than once thought, even those passionate about founding a new venture, end up not starting a new business because of the vast challenges. This study provides new insights into how and when passionate nascent founders actually engage in new venture creation behavior. Applying a conditional moderated mediation analysis to a sample of 493 Belgian nascent entrepreneurs, we find that passionate nascent founders develop strategic action plans to reach their desired complex goal of starting a new venture.

Purpose This study aimed to evaluate the accuracy of detecting vertical root fractures in Biodentine™-filled teeth using the Promax 3Dmax cone-beam computed tomography (CBCT) unit compared to periapical radiographs. It tested hypotheses regarding CBCT’s diagnostic superiority in non-root-filled and Biodentine™-root-filled maxillary central incisors and assessed the impact of smaller field of view and lower intensity settings on detection accuracy.

B cell depletion by the anti-CD20 antibody ocrelizumab is effective in relapsing-remitting (RR) and primary progressive (PP) multiple sclerosis (MS). We investigated immunological changes in peripheral blood of a real- world MS cohort after 6 and 12 months of ocrelizumab. All RRMS and most PPMS patients (15/20) showed treatment response. Ocrelizumab not only reduced CD20+ B cells, but also numbers of CD20+T cells. Absolute numbers of monocytes, dendritic cells and CD8+T cells were increased, while CD56hi natural killer cells were reduced after ocrelizumab.